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pentobarbital will minimize the extent or effect of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will reduce the level or result of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.Immediately after stopping a CYP3A4 inducer, as th